Methylisothiazolinone(C4H5NOS) can be applied in cream, dew liquid, shampoo, hair conditioner, eye cosmetics, liquid cosmetics and other cosmetics. But it inhibits the tyrosine phosphorylation of FAK by another kinase called Src, preventing the growth of axons and dendrites, at least in culture. These findings were published in the Journal of Pharmacology and Experimental Therapeutics.
The toxic actions of Methylisothiazolinone on developing neurons occurs at much lower concentrations than those inducing lethal injury (1-3 micromolar).
CMIT is even more potent, working at concentrations as low as 0.1 micromolar. One micromolar is approximately 0.115 parts per million.
Nanjing Jiancheng Chemical Industrial Co.Ltd founded in 1998, is one of the largest preservative manufacture in China. The Factory mainly produces all kinds of preservatives, which widely applied in cosmetics, medicine, and food industry.
Our main products are Diazolidinyl urea, Imidazolidinyl urea, Methylparaben, Ethylparaben, Propylparaben, Butylparaben, Bronopol, Allantoin, Germall Plus, JMB, JMC, JMBP and so on. Our products are well exported to all over the world, such as North America, Europe and Southeast Asia, etc.
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